Which of the following statements correctly compares water-soluble hormones with lipid-soluble hormones?
A)Both types of hormones are carried in the blood attached to a carrier protein.
B)Both types of hormone almost always stimulate increases in mRNA transcription.
C)Only water-soluble hormones use second messengers.
D)Only water-soluble hormones require a receptor.
E)Lipid-soluble hormones are not found in the bloodstream.

Question

Quizplus · Accepted Answer

Water-soluble hormones bind to receptors on the cell membrane and activate intracellular signaling pathways that involve second messengers such as cyclic AMP or calcium ions. Lipid-soluble hormones diffuse into the target cells and bind to intracellular receptors, which in turn regulate gene transcription without involving second messengers. Therefore, only water-soluble hormones use second messengers.

Which of the Following Statements Correctly Compares Water-Soluble Hormones with Lipid-Soluble