Which Choice Lists Two Effects Expected from the Depletion of the Ozone

Which choice lists two effects expected from the depletion of the ozone layer? 1) asthma 2) lung cancer 3) skin cancer 4) genetic mutations 5) emphysema

A) 1 and 5
B) 2 and 3
C) 3 and 5
D) 3 and 4
E) 4 and 5