Large quantities of antibodies that react to the second entry of antigen and lead to formation of antigen-antibody complexes that deposit in basement membranes occur in
A)serum sickness.
B)delayed hypersensitivity.
C)anaphylaxis.
D)hemolytic disease of the newborn.
E)All of the choices are correct.

Question

Quizplus · Accepted Answer

Serum sickness is a type III hypersensitivity reaction in which large quantities of antibodies form immune complexes with antigens and deposit in basement membranes, leading to tissue damage. The antibodies react to the second entry of the antigen and lead to the formation of antigen-antibody complexes. Delayed hypersensitivity (answer B) is a type IV hypersensitivity reaction that occurs 24-72 hours after exposure to an antigen. Anaphylaxis (answer C) is a type I hypersensitivity reaction that occurs rapidly and can be life-threatening. Hemolytic disease of the newborn (answer D) is not a type III hypersensitivity reaction but is caused by maternal antibodies attacking fetal red blood cells. Therefore, the correct answer is A, serum sickness.

Large Quantities of Antibodies That React to the Second Entry