If cells in the process of dividing are subjected to colchicines,a drug that interferes with the functioning of the spindle fibers,at which stage will mitosis be arrested?
A) anaphase
B) prophase
C) telophase
D) metaphase
E) interphase

Question

Quizplus · Accepted Answer

Colchicine interferes with the assembly of the spindle fibers, which are responsible for the separation of the chromosomes. During metaphase, the chromosomes line up at the equator of the cell and are attached to spindle fibers. Without functioning spindle fibers, the chromosomes cannot separate, and the cell cycle will be arrested at this stage. Therefore, the correct answer would be D) metaphase.

If Cells in the Process of Dividing Are Subjected to Colchicines,a