Which of the following is a strong candidate to act as a retrograde messenger from the dendrite to the terminal button?
A) glutamate
B) nitric oxide
C) nitrous oxide
D) norepinephrine
E) NMDA

Question

Quizplus · Accepted Answer

Nitric oxide (NO) is a strong candidate to act as a retrograde messenger from the dendrite to the terminal button. It is a gas and can easily diffuse across the membrane, making it an efficient messenger. It is also produced in postsynaptic neurons and can regulate presynaptic transmission by activating guanylate cyclase and increasing cGMP levels, leading to a decrease in neurotransmitter release. Glutamate and NMDA are excitatory neurotransmitters, and norepinephrine is a neuromodulator that affects the activity of other neurotransmitters. Nitrous oxide is not known to act as a retrograde messenger in the nervous system.

Which of the Following Is a Strong Candidate to Act