What pathologic alteration produces tremors at rest, rigidity, akinesia, and postural abnormalities?
A)Atrophy of neurons in the caudate that produce serotonin
B)Atrophy of neurons in the putamen that produce gamma-aminobutyric acid (GABA)
C)Atrophy of neurons in the substantia nigra that produce dopamine
D)Atrophy of neurons in the hypothalamus that produce acetylcholine

Question

Quizplus · Accepted Answer

The hallmark characteristics of Parkinson disease are a result of a loss of dopaminergic pigmented neurons in the substantia nigra (SN) pars compacta with dopaminergic deficiency in the putamen portion of the striatum (the striatum includes the putamen and caudate nucleus).

What Pathologic Alteration Produces Tremors at Rest, Rigidity, Akinesia, and Postural