What is a major determinant of the resting membrane potential necessary for transmission of nerve impulses? A) The ratio between intracellular sodium (Na⁺)and extracellular sodium B) The ratio between intracellular potassium (K⁺)and extracellular potassium C) The ratio between intracellular sodium (Na⁺)and extracellular potassium (K⁺) D) The ratio between intracellular potassium (K⁺)and extracellular sodium (Na⁺)

Question

Quizplus · Accepted Answer

The resting membrane potential necessary for transmission of nerve impulses is primarily determined by the ratio between intracellular potassium and extracellular potassium (K⁺). This is because the cell membrane is more permeable to potassium ions than to sodium ions, leading to a higher concentration of potassium inside the cell and a lower concentration outside. This uneven distribution creates an electrical potential across the membrane, with the inside of the cell being negative relative to the outside. This potential is known as the resting membrane potential, and it is essential for the transmission of nerve impulses. Therefore, the correct answer is B, the ratio between intracellular potassium and extracellular potassium.

What Is a Major Determinant of the Resting Membrane Potential