All of the following is true for glutamate except:
A) Ionotropic receptors allow positively charged ions into the neuron.
B) All of the receptors for glutamate produce excitatory effects.
C) Glutamate is released from pyramidal neurons.
D) Glutamate is the most prominent excitatory neurotransmitter.

Question

Quizplus · Accepted Answer

Not all receptors for glutamate produce exclusively excitatory effects. While glutamate is primarily an excitatory neurotransmitter and its receptors generally mediate excitatory neurotransmission, the effects can vary based on the receptor subtype and cellular context. For example, metabotropic glutamate receptors can modulate neuronal excitability in more complex ways, sometimes even reducing excitability depending on their location and the signaling pathways they engage.

All of the Following Is True for Glutamate Except