The manifestation that would require immediate investigation in a client with infectious mononucleosis is A) abdominal pain. B) joint discomfort. C) leukocyte count of 12,000/mm³. D) sore throat.

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When infectious mononucleosis is severe, the client may develop splenic rupture resulting from the infiltration of the spleen by massive numbers of lymphocytes. Joint discomfort is not a typical complaint, although muscle aches and pains are. The leukocyte count typically ranges from 12,000 to 20,000/mm³. Sore throats are common in mononucleosis.

The Manifestation That Would Require Immediate Investigation in a Client