Cholera toxin polypeptide A binds to surface gangliosides on target cells.If the gangliosides were removed,
A)polypeptide A would bind to target cells.
B)polypeptide A would enter the cells.
C)polypeptide B would not be able to enter the cells.
D)Vibrio would not produce cholera toxin.
E)Vibrio would bind to target cells.

Question

Quizplus · Accepted Answer

Cholera toxin is composed of two subunits, A and B. Subunit B binds to surface receptors on the target cell, while subunit A enters the cell and causes the toxic effects. If the gangliosides were removed, subunit B would not be able to bind to the target cells, preventing subunit A from entering the cells and exerting its toxic effects. Therefore, the best choice is C.

Cholera Toxin Polypeptide a Binds to Surface Gangliosides on Target