Ribosomes that do not anchor on the surface of the rough endoplasmic reticulum during translation most probably
A)are synthesizing cytoplasmic proteins.
B)have a defect in ribosomal proteins that allow attachment to the surface.
C)have a signal peptidase error.
D)do not make the appropriate anchor protein.
E)all of the above

Question

Quizplus · Accepted Answer

Ribosomes that do not anchor on the surface of the rough endoplasmic reticulum (RER) during translation are likely synthesizing cytoplasmic proteins. The RER is responsible for the synthesis and modification of proteins that are destined for secretion or insertion into the plasma membrane. Ribosomes that do not anchor on the RER surface are not involved in this process, and instead are free to synthesize proteins that are used within the cytoplasm. The other options presented (B, C, D, and E) are all possibilities, but they are less likely than option A.

Ribosomes That Do Not Anchor on the Surface of the Rough