Using the techniques of genetic engineering,you design a cytoplasmic protein you want to accumulate within the ER of yeast cells. To accomplish this goal,you need to
A)do nothing; all proteins go through the ER.
B)incorporate the appropriate mannose-6-phosphate groups.
C)incorporate the appropriate DNA sequence with the proper signal.
D)incorporate radioactive amino acids into the protein.
E)incorporate the appropriate lipid groups into the lipoprotein.

Question

Quizplus · Accepted Answer

To ensure that a protein is targeted to the ER, it needs to contain the appropriate DNA sequence with the proper signal. This signal sequence codes for a specific amino acid sequence that targets the protein to the ER. Mannose-6-phosphate groups are targeted to the lysosome, not the ER. Radioactive amino acids and lipid groups do not play a role in targeting proteins to the ER.

Using the Techniques of Genetic Engineering,you Design a Cytoplasmic Protein