Which of the following definitions accurately represents the concept of expansion?
A)The phenotype of a genetic condition is expressed with greater severity and at earlier ages with succeeding generations.
B)The number of trinucleotide repeat sequences within the noncoding region of a specific gene allele is increased.
C)The number of copies of a specific gene allele is amplified on one chromosome of a homologous pair.
D)A specific gene allele has at least two copies of every exon within the gene.

Question

Quizplus · Accepted Answer

Expansion is an increase, usually of trinucleotide repeat sequences within a gene. The definition of response A is that of anticipation. The definition of response C is amplification. Response D is just a mutation that would result in either an inappropriate protein or no protein produced.

Which of the Following Definitions Accurately Represents the Concept of Expansion