You are testing the effects of central administration of inhibitors of fatty acid oxidation on hypothalamic activity. Which of the following neuropeptides would you expect to see expressed at elevated levels in response to the actions of the inhibitor?
A) agouti-related peptide, AgRP
B) cocaine- and amphetamine-regulated transcript, CART
C) galanin
D) melanin-concentrating hormone, MCH
E) neuropeptide Y, NPY

Question

Quizplus · Accepted Answer

Melanin-concentrating hormone (MCH) expression is responsive to differences in fuel source availability in the brain. Pharmacological inhibition or activation of glucose metabolism exerts no effect on the expression of MCH, however, inhibition of fatty acid oxidation results in increased expression and release of the hormone

You Are Testing the Effects of Central Administration of Inhibitors