In the synthesis of pyrimidines, which of the following molecules is a direct precursor of the pyrimidine ring?
A) aspartate
B) fumarate
C) glutamate
D) glycine
E) 5-phosphoribosyl-1-pyrophosphate

Question

Quizplus · Accepted Answer

Aspartate is a direct precursor in the synthesis of the pyrimidine ring, contributing atoms to the ring structure. Synthesis of the pyrimidines requires 1 mole of glutamine, 1 mole of ATP, and 1 mole of CO₂ (which form carbamoyl phosphate) and 1 mole of aspartate. An additional mole of glutamine and ATP are required in the conversion of UTP to CTP

In the Synthesis of Pyrimidines, Which of the Following Molecules