Which of the following components of the electron transport system is inhibited by oligomycin?
A) ATP synthase
B) complex I
C) complex II
D) complex III
E) complex IV

Question

Quizplus · Accepted Answer

Oligomycin specifically inhibits ATP synthase, preventing the synthesis of ATP by blocking the proton channel of the enzyme. Oligomycin is a natural antibiotic isolated from Streptomyces diastatochromogenes which inhibits mitochondrial ATP synthase. It inhibits the ATPsynthase by binding to the oligomycin sensitivity-conferring protein (OSCP) of the F₀ portion of the complex.

Which of the Following Components of the Electron Transport System