The Reactions of the PPP Using Glucose 6-Phosphate as the Initial

The reactions of the PPP using glucose 6-phosphate as the initial substrate are best described by which of the following statements?

A) they are not required for the production of NADPH in the mature erythrocyte
B) they are required for the metabolism of glucose in the muscles
C) they generate 2 moles of adenosine triphosphate per mole of G6P metabolized to ribulose 5-phosphate.
D) they occur in the matrix of mitochondria
E) they produce 2 moles of NADPH for each mole of CO₂ released