Which of the following is the mechanism by which allosteric effectors influence enzymatic activity?
A) binding at the catalytic site
B) changing the conformation of the enzyme
C) forming high-energy complexes with substrate
D) increasing hydration of the active site
E) protecting against degradation of the enzyme

Question

Quizplus · Accepted Answer

Allosteric effectors bind to a site other than the catalytic site, causing a conformational change in the enzyme that affects its activity.  Allosteric enzymes are enzymes whose conformation changes upon binding of an allosteric effector. This binding results in an apparent change in binding affinity in the enzyme at a different ligand-binding site. This action at a distance through binding of one ligand (or allosteric effector) affecting the binding of another at a distinctly different site is the essence of the allosteric concept.

Which of the Following Is the Mechanism by Which Allosteric