A 12-Year-Old Boy Has Suffered from Chronic Sinopulmonary Disease Including

A 12-year-old boy has suffered from chronic sinopulmonary disease including persistent infection of the airway with Pseudomonas aeruginosa. He has constant and chronic sputum production because of the airway infection. Additionally, he suffers from gastrointestinal (GI) and nutritional abnormalities that include biliary cirrhosis, meconium ileus, and pancreatic insufficiency. The symptoms are classical for which of the following disorders?

A) congenital adrenal hyperplasia
B) cystic fibrosis
C) renal Fanconi syndrome
D) sickle cell anemia
E) Tay-Sachs disease