Elsewhere in the paper,Chen et al.state that "BDNF is encoded by a complex gene with four well-characterized promoters that give rise to at least eight different mRNAs." What mechanism could account for the production of these different BDNF mRNAs?
A)chromatin condensation control
B)alternative splicing
C)translational control
D)post-translational control

Question

Quizplus · Accepted Answer

The production of different BDNF mRNAs is most likely due to alternative splicing, as the four promoters can generate different transcript variants through exon skipping, alternative 5' and 3' splice site selection, and intron retention. This results in different isoforms of BDNF protein with distinct functional properties.

Elsewhere in the Paper,Chen Et Al