When a product binds to an allosteric enzyme to slow its reaction, it does which of the following?
A) binds to the active site, blocking the binding of substrate
B) binds to a site other than the active site, changing the shape of the active site and decreasing the binding of substrate
C) binds to the substrate, blocking its binding of the active site
D) binds to the product production site, stopping the production of product

Question

Quizplus · Accepted Answer

Allosteric regulation involves the binding of a molecule at a site other than the enzyme's active site, which induces a conformational change that affects the enzyme's activity. In this case, the product binds to an allosteric site, altering the shape of the active site and thus decreasing the enzyme's ability to bind to its substrate.

When a Product Binds to an Allosteric Enzyme to Slow