Fragile X syndrome is a relatively recent discovery in the list of chromosomal disorders. Researchers have found that Fragile X
A) is similar in transmission to Down syndrome.
B) affects females more adversely in terms of cognitive and physical development.
C) occurs more likely in males than females.
D) is related to the Y chromosome in males.
E) is passed on from the male carrier only.

Question

Quizplus · Accepted Answer

Fragile X syndrome is more likely to occur in males than females due to its association with the X chromosome. Males have one X and one Y chromosome, so a single altered gene on the X chromosome can cause the disorder. Females have two X chromosomes, so a mutation in one of the X chromosomes may be partially compensated for by the normal gene on the other X chromosome, making the condition less likely or less severe in females.

Fragile X Syndrome Is a Relatively Recent Discovery in the List