Which of the following is true about Marfan syndrome?
A) The cause is an autosomal recessive mutation.
B) The affected gene produces a defective form of the protein actin.
C) Connective tissues are weakened.
D) One in 5,000 men are affected.
E) Those affected are often very short and have mental impairments.

Question

Quizplus · Accepted Answer

Marfan syndrome is a genetic disorder that affects the body's connective tissues, causing them to weaken. This can lead to a variety of symptoms, including abnormalities in the skeleton, eyes, and cardiovascular system. It is caused by a mutation in the FBN1 gene, which codes for the protein fibrillin. The disorder is inherited in an autosomal dominant pattern, which means that if one parent has the condition, there is a 50% chance each of their children will inherit it. The prevalence is estimated to be around 1 in 5,000 to 10,000 individuals worldwide, and there is no cure for the disorder.

Which of the Following Is True About Marfan Syndrome