In E-LTP, what happens to silent dendritic spine synapses when functional synapses are subjected to LTP? A) LTP leads to AMPA receptor removal from the membrane and receptor degradation. B) There is an influx of Ca²⁺ ions into the NMDA receptor which activates AMPA receptors thereby making the silent synapses functional. C) AMPA receptors in the silent synapses move into spine membrane thereby making the synapses functional. D) Functional synapses suppress the transport of AMDA into silent synapses during LTP.

Question

Quizplus · Accepted Answer

During LTP, AMPA receptors in the silent synapses move into the spine membrane, thereby making the synapses functional. This process is known as AMPA receptor trafficking. Option A is incorrect as it describes AMPA receptor removal and degradation, which is not the case. Option B is incorrect as it describes the mechanism of NMDA receptor activation but does not explain what happens to the silent synapses. Option D is incorrect as it describes a suppression of AMPA transport, which is not supported by current research.

In E-LTP, What Happens to Silent Dendritic Spine Synapses When