Termination of translation and release of the polypeptide chain occur when
A) tRNA binds to a termination codon via a complementary anticodon but lacks an amino acid.
B) a protein release factor binds to the termination codon.
C) a tRNA with a complementary anticodon binds to a termination codon, and a release factor bound to the CCA end releases the chain.
D) a small molecule shaped like puromycin binds to the termination codon.

Question

Quizplus · Accepted Answer

Termination of translation and release of the polypeptide chain occur when a protein release factor binds to the termination codon, causing the release of the polypeptide chain from the ribosome. Choice A is incorrect because a tRNA binding to a termination codon without an amino acid would not lead to termination and release. Choice C is partially correct, but it is the release factor, not the tRNA, that releases the polypeptide chain. Choice D is incorrect because puromycin binding to the termination codon would cause premature chain termination, not normal termination and release.

Termination of Translation and Release of the Polypeptide Chain Occur