Which Statement Most Accurately Describes Substance Addiction

Which statement most accurately describes substance addiction?

A) A chronic, relapsing brain disease associated with craving and a lack of control over use of a substance.
B) A disorder associated with tolerance to a substance as well as withdrawal symptoms if use is abruptly discontinued.
C) Behaviors associated with habitual use of a substance for the single purpose of altering one's mood, emotion, or state of consciousness.
D) A behavioral disorder associated with selected personality features.