The HPA axis involves initial activation of the:
A) hypothalamus
B) hippocampus
C) hindbrain
D) heart

Question

Quizplus · Accepted Answer

The HPA (hypothalamic-pituitary-adrenal) axis involves initial activation of the hypothalamus. The hypothalamus releases corticotropin-releasing hormone (CRH) which stimulates the pituitary gland to release adrenocorticotropic hormone (ACTH), which in turn activates the adrenal glands to release cortisol, a stress hormone. The hippocampus and hindbrain are not directly involved in the HPA axis. The heart may be impacted by the HPA axis as cortisol can affect cardiovascular functioning, but it is not the initial site of activation.

The HPA Axis Involves Initial Activation of The