How does transplatin stop DNA replication?
A)Through its interaction with guanines in the DNA
B)By binding to the minor groove of DNA
C)By forcing a kink in the DNA that cannot be repaired
D)It doesn't; transplatin is not a useful anti-cancer drug.

Question

Quizplus · Accepted Answer

Transplatin, unlike its isomer cisplatin, does not effectively stop DNA replication because it does not form the same type of cross-links with DNA. This makes it much less useful as an anti-cancer drug compared to cisplatin.

How Does Transplatin Stop DNA Replication