Which enzyme deficiency results in the accumulation of fructose-1-phosphate?
A) glucokinase
B) arginase
C) phenylalanine hydroxylase
D) lipase
E) aldolase B

Question

Quizplus · Accepted Answer

The enzyme deficiency that results in the accumulation of fructose-1-phosphate is aldolase B deficiency, also known as hereditary fructose intolerance. This condition is characterized by the inability to metabolize fructose due to a deficiency in the enzyme aldolase B, which catalyzes the cleavage of fructose-1-phosphate. This results in the accumulation of fructose-1-phosphate and depletion of other metabolites, leading to hypoglycemia, liver and kidney damage, and other symptoms.

Which Enzyme Deficiency Results in the Accumulation of Fructose-1-Phosphate