Inhibition of which of the following processes would reduce or eliminate generation of a proton-motive force in mitochondria?
A) the flow of protons through ATP synthase down their concentration gradient
B) the reduction of NAD+ by the first electron carrier in the electron transport chain
C) lowering of pH in the mitochondrial matrix
D) pumping of hydrogen ions from the mitochondrial matrix across the inner membrane and into the intermembrane space

Question

Quizplus · Accepted Answer

The proton-motive force is generated by the pumping of hydrogen ions from the mitochondrial matrix into the intermembrane space, creating a gradient. Inhibiting this process would prevent the formation of the gradient necessary for ATP synthesis.

Inhibition of Which of the Following Processes Would Reduce or Eliminate