What is the basis for the difference in how the leading and lagging strands of DNA molecules are synthesized?
A) The The origins of replication occur only at the 5' end.
B) Helicases and single-strand binding proteins work at the 5' end.
C) DNA polymerase can join new nucleotides only to the 3' end of a pre-existing strand, and the strands are antiparallel.
D) DNA ligase works only in the 3' → 5' direction.

Question

Quizplus · Accepted Answer

DNA polymerase adds nucleotides only to the 3' end of a growing strand, and because the two strands of DNA are antiparallel, this necessitates different processes for synthesizing the leading and lagging strands.

What Is the Basis for the Difference in How the Leading