DNA is isolated from bacteria undergoing DNA replication. After heat treatment to disrupt H-bonds the DNA is centrifuged and it separates into two classes. One class of DNA includes very large molecules (thousands or even millions of nucleotides long), and the other includes short stretches of DNA (several hundred to a few thousand nucleotides in length). Which types of DNA do the two classes most likely represent?
A) leading strands and Okazaki fragments
B) lagging strands and Okazaki fragments
C) Okazaki fragments and Origin of replication
D) leading strands and fragments generated due to replication errors

Question

Quizplus · Accepted Answer

The very large molecules represent leading strands, which are synthesized continuously during DNA replication, while the short stretches of DNA are Okazaki fragments, which are synthesized discontinuously on the lagging strand.

DNA Is Isolated from Bacteria Undergoing DNA Replication