The sequence of nucleotides below is present at a DNA location where the chain opens to form a replication fork:
3' C C T A G G C T G C A A T C C 5'
An RNA primer is formed starting at the underlined T (T) of the template. Which of the following represents the primer sequence?
A) 5' A G C C U A G G 3'
B) 5' A C G T T A G G 3'
C) 5' A C G U U A G G 3'
D) 5' A G C C T A G G 3'

Question

Quizplus · Accepted Answer

RNA primers are synthesized as complements to the DNA template strand, but with uracil (U) replacing thymine (T). The sequence complementary to 3' CCTAGG 5' is 5' GGAUCC 3', which matches option C when considering RNA nucleotides (U instead of T).

The Sequence of Nucleotides Below Is Present at a DNA