Carl has frequent infections and, after testing, has been diagnosed with a genetic form of agammaglobulinemia (meaning no gamma globulins in the blood). Why would this condition result in difficulty fighting off infections?
A) His B cells can't make antibodies, so he has no humoral immune response.
B) His T cells over-react, resulting in activation of autoantibodies.
C) His macrophages are overproducing cytokines, making the immune response ineffective.
D) He is unable to produce T cells, so he has no cellular immune response.

Question

Quizplus · Accepted Answer

Agammaglobulinemia affects B cells' ability to produce antibodies, crucial for the humoral immune response that targets pathogens in body fluids. Without these antibodies, the body struggles to fight off infections.

Carl Has Frequent Infections And, After Testing, Has Been Diagnosed