Once the Substrate Moves into the Active Site of the Enzyme

Once the substrate moves into the active site of the enzyme,

A) the enzyme breaks the substrate into three products.
B) the two molecules fuse together to form the product.
C) the enzyme alters in shape to more closely fit the substrate.
D) the substrate alters shape to more closely fit the active site.
E) the substrate and enzyme both alter shape to fit together.