You describe for your patient the sequence of events that occurs when a B cell is activated. Please select the correct order of statements.
1) TH cells recognize the presented antigen-MHC complex on the B cell and bind to it.
2) B cell receptor binds to an antigen and the antigen is internalized by endocytosis.
3) The bound TH delivers cytokines to the B cell that initiate the process of clonal expansion of that particular B cell.
4) The antigen is degraded and peptide fragments are expressed at the B cell membrane with MHC class II molecules.
A) 1, 2, 3, 4
B) 4, 3, 1, 2
C) 1, 3, 2, 4
D) 2, 3, 1, 4
E) 2, 4, 1, 3

Question

You describe for your patient the sequence of events that occurs when a B cell is activated. Please select the correct order of statements.
1) TH cells recognize the presented antigen-MHC complex on the B cell and bind to it. 
2) B cell receptor binds to an antigen and the antigen is internalized by endocytosis.
3) The bound TH delivers cytokines to the B cell that initiate the process of clonal expansion of that particular B cell.
4) The antigen is degraded and peptide fragments are expressed at the B cell membrane with MHC class II molecules.
A) 1, 2, 3, 4
B) 4, 3, 1, 2
C) 1, 3, 2, 4
D) 2, 3, 1, 4
E) 2, 4, 1, 3

Quizplus · Accepted Answer

The correct sequence starts with the B cell receptor binding to an antigen (2), followed by internalization and presentation of the antigen with MHC class II (4), then T helper (TH) cells recognizing the antigen-MHC complex (1), and finally, the TH cells delivering cytokines to initiate clonal expansion (3).

You Describe for Your Patient the Sequence of Events That