The advantage(s) of second-generation DNA sequencing compared to the Sanger method are the result of
A) miniaturization of reaction size.
B) increased computing power.
C) increased length of DNA sequences obtained.
D) miniaturization of reaction size and increased computer power.

Question

Quizplus · Accepted Answer

Second-generation DNA sequencing technologies, such as Illumina and Roche 454, use miniaturized reaction sizes and produce massive amounts of data that require increased computing power for analysis. As a result, they can generate much longer DNA reads than the Sanger method, making them better suited for whole-genome sequencing and other applications that require large amounts of sequencing data.

The Advantage(s) of Second-Generation DNA Sequencing Compared to the Sanger