What is responsible for degrading antigens located in the cytosol of antigen-presenting cells into short peptides?
A)uncomplexed proteases floating free in the cytoplasm
B)proteases that are part of proteasomes
C)proteases embedded in the nuclear membrane
D)the acidic environment of the lysosome lumen
E)hydrolytic enzymes of the lysosomal lumen

Question

Quizplus · Accepted Answer

Proteasomes, which are large protein complexes, are responsible for degrading antigens located in the cytosol of antigen-presenting cells into short peptides. Proteasomes are made up of proteases, which specifically cleave peptide bonds in proteins.

What Is Responsible for Degrading Antigens Located in the Cytosol