The amount of enzyme activity in a cell that is homozygous for a mutant allele is 0 units. The amount of enzyme activity in a cell homozygous for the WT allele is 200 units. The amount of enzyme activity in a heterozygote is 0 units. What type of allele is the mutant allele?
A) neomorphic
B) hypermorphic
C) hypomorphic
D) null/ amorphic
E) dominant negative

Question

Quizplus · Accepted Answer

The mutant allele is dominant negative because it completely suppresses the enzyme activity even in the presence of a wild-type allele, indicating it interferes with the function of the normal protein.

The Amount of Enzyme Activity in a Cell That Is