The amount of enzyme activity in a cell that is homozygous for a mutant allele is 400 units. The amount of enzyme activity in a cell homozygous for the WT allele is 200 units. The amount of enzyme activity in a heterozygote is 300 units. What type of allele is the mutant allele?
A) hypermorphic
B) hypomorphic
C) neomorphic
D) null/ amorphic
E) dominant negative

Question

Quizplus · Accepted Answer

Hypermorphic alleles result in an increase in the normal function of the gene product, which is consistent with the observed increase in enzyme activity in cells homozygous for the mutant allele compared to those homozygous for the wild-type allele.

The Amount of Enzyme Activity in a Cell That Is