Which of the following statements describes a key component of the induced fit hypothesis of enzyme catalysis?
A) Substrate binds to an allosteric site rather than to the active site of an enzyme.
B) Binding of an activator molecule changes the shape of the active site of an enzyme.
C) The conformation of the active site is determined by the tertiary or quaternary structure of the enzyme.
D) Binding of substrate to the active site changes the shape of the active site of an enzyme.

Question

Quizplus · Accepted Answer

The induced fit hypothesis of enzyme catalysis proposes that the binding of a substrate to the active site of an enzyme causes a change in the shape of the active site to better fit and stabilize the substrate. Therefore, binding of substrate to the active site changes the shape of the active site of an enzyme, making choice (D) the correct answer. The other choices do not fully describe the induced fit hypothesis.

Which of the Following Statements Describes a Key Component of the Induced