Arrange the following events of endochondral ossification in the proper sequence:
(1) Cartilage matrix is calcified and chondrocytes die.
(2) Chondrocytes hypertrophy.
(3) Cartilage model is formed.
(4) Osteoblasts deposit bone on the surface of the calcified cartilage of the primary ossification center.
(5) Blood vessels from the periosteum invade calcified cartilage bringing in osteoblasts and osteoclasts.
A) 3, 2, 1, 5, 4
B) 3, 2, 5, 4, 1
C) 3, 2, 5, 1, 4
D) 3, 5, 2, 4, 1
E) 1, 3, 4, 5, 2

Question

Quizplus · Accepted Answer

Endochondral ossification begins with the formation of a cartilage model (3), followed by the hypertrophy of chondrocytes (2). The cartilage matrix then calcifies and the chondrocytes die (1). Blood vessels invade the calcified cartilage, bringing osteoblasts and osteoclasts (5), and finally, osteoblasts deposit bone on the surface of the calcified cartilage of the primary ossification center (4).

Arrange the Following Events of Endochondral Ossification in the Proper