Assume we could alter the conditions in the duodenum. Which of the following would be consistent with inserting a large volume of highly acidic chyme which contained a large amount of fat?
(1) Decreased gastric acid secretion
(2) Increased bile production
(3) Increased pancreatic bicarbonate production and pancreatic enzyme secretion
(4) Increased secretin and cholecystokinin
A) 1, 2, 3, 4
B) 1, 2, 3
C) 2, 3, 4
D) 1, 3, 4
E) 1, 2, 4

Question

Quizplus · Accepted Answer

Inserting a large volume of highly acidic chyme with a lot of fat into the duodenum would lead to decreased gastric acid secretion due to negative feedback mechanisms (1), increased bile production to emulsify the fats (2), increased pancreatic bicarbonate production to neutralize the acid and pancreatic enzyme secretion to digest the fats (3), and increased secretin and cholecystokinin release in response to the fats and acidity to stimulate these processes (4).

Assume We Could Alter the Conditions in the Duodenum