Which of the following statements explaining the mechanism of action of telomerase is correct? (Select all that apply.)
A) The extension of telomeres via telomerase occurs at the 3ʹ overhang with a G-rich sequence.
B) Telomerase carries a short single-stranded DNA component that is used as a template to extend the telomere.
C) The extension of telomeres via telomerase occurs at the 5ʹ end, where DNA polymerase cannot add a new deoxynucldotide after the removal of the very last RNA primer.
D) The extension at the 3ʹ overhang is followed by the extension of 5ʹ complementary strand via a currently unknown mechanism.
E) Telomerase finishes complementary base pairing of the 5ʹ complementary strand.
Correct Answer:
Verified
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