If the frequency of an autosomal recessive trait in humans is 1 out of 100 births, what would be the expected frequency of heterozygote carriers for the trait if we assume that the gene is in Hardy-Weinberg equilibrium?
A)0.01
B)0.10
C)0.18
D)0.81

Question

Quizplus · Accepted Answer

In Hardy-Weinberg equilibrium, the frequency of the recessive trait (q^2) is 0.01, so q = 0.1. The frequency of heterozygote carriers (2pq) is 2 * (0.9) * (0.1) = 0.18.

If the Frequency of an Autosomal Recessive Trait in Humans