What is a major advantage of using a modifier screen as opposed to a primary screen?
A)Modifier screens can be used to identify pleiotropic genes.
B)Modifier screens are easier to perform.
C)Modifier screens use a random selection of flies based on their morphology and therefore should identify all genes involved in development.
D)Modifier screens are performed with chemically mutagenized flies so all genes that affect development should be identified more rapidly than screening for spontaneous mutants.

Question

Quizplus · Accepted Answer

Modifier screens are specifically designed to identify genes that modify the phenotype of a known mutation, which can include pleiotropic genes that affect multiple traits or pathways. This is a major advantage over primary screens, which aim to identify genes based on a specific phenotype without prior knowledge of genetic interactions.

What Is a Major Advantage of Using a Modifier Screen