The classical pathway for complement activation is initiated by
A) factors released from damaged tissues.
B) antigen-antibody reactions.
C) factors released from phagocytes.
D) lipid- carbohydrate complexes and C3.
E) C5-C9.

Question

Quizplus · Accepted Answer

The classical pathway for complement activation is initiated by antigen-antibody reactions, specifically IgG or IgM binding to an antigen. This triggers a complex cascade of enzymatic reactions that ultimately results in the formation of the membrane attack complex (MAC) to lyse foreign cells.

The Classical Pathway for Complement Activation Is Initiated by