While performing a 100-cell manual WBC differential, the laboratory professional observes Dohle bodies, toxic granulation and vacuoles in many neutrophils. This would suggest:
A) Megaloblastic anemia
B) Acute leukemia
C) Bacterial infection
D) Chronic leukemia

Question

Quizplus · Accepted Answer

Dohle bodies, toxic granulation, and vacuoles are all characteristic findings in neutrophils during bacterial infections. Megaloblastic anemia is associated with macrocytic RBCs and hyper-segmented neutrophils, while acute and chronic leukemias typically involve abnormal blasts or immature cells in the peripheral blood.

While Performing a 100-Cell Manual WBC Differential, the Laboratory Professional