Which of the following lab tests is used to confirm G6PD deficiency?
A) Fluorescent spot test
B) PB smear
C) NADP rate reduction test
D) Reticulocyte count

Question

Quizplus · Accepted Answer

The NADP rate reduction test is the most specific and sensitive test for G6PD deficiency. The test measures the rate of NADP reduction to NADPH in G6PD-normal and deficient red blood cells. G6PD-deficient individuals will have reduced levels of NADPH, indicating a deficiency. The fluorescent spot test is less specific and should only be used for screening. PB smear and reticulocyte count may show signs of hemolysis but are not specific for G6PD deficiency.

Which of the Following Lab Tests Is Used to Confirm