Based on the effects of lin-4 and lin-14 mutations in C.elegans,worms in which there is an overexpression of the lin-14 gene would
A) keep repeating the first larval stage.
B) skip the first larval stage and move right onto the second.
C) methylate DNA inappropriately.
D) fail to methylate DNA when appropriate.
E) overexpress CREB.

Question

Quizplus · Accepted Answer

The lin-4 gene normally inhibits the expression of lin-14, which is required for progression through the first larval stage in C. elegans. A mutation in lin-4 causes lin-14 to be expressed inappropriately, resulting in a failure to progress beyond the first larval stage. Therefore, overexpression of the lin-14 gene would have the opposite effect and lead to repeating the first larval stage.

Based on the Effects of Lin-4 and Lin-14 Mutations in C.elegans,worms